Semilobar holoprosencephaly is a subtype of holoprosencephaly characterised by incomplete forebrain division. It is intermediate in severity, being worse than. a Unidad de Diagn??stico por Imagen (MEDTEC).??rea de Servicio Compartido de Radiolog??a. Complejo Hospitalario Universitario de Vigo. Vigo. Espa??a. Diagnóstico prenatal de trisomía 21 y holoprosencefalia semilobar. with both cerebral ventricles dilated, semilobar holoprosencephaly and cleft lip and palate.

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Please refer on the general article of holoprosencephaly. In contrast to alobar holoprosencephaly, facial malformations are usually mild or absent 5. As with all hollprosencefalia of holoprosencephaly, it is a rare congenital brain malformation in which there is failure of complete separation of the two hemispheres and failure of transverse cleavage into diencephalon holoprrosencefalia telencephalon. For a general discussion of epidemiology, clinical presentation and pathology, please refer to the article on holoprosencephaly.


As will most cerebral structural congenital abnormalities, semilobar holoprosencephaly is visible on all modalities, but in general is identified on antenatal ultrasound, and best characterised by MRI. The basic structure of the cerebral lobes are present, but are fused most commonly anteriorly and at the thalami and there is partial diverticulation of brain dorsal cyst. In addition, this condition is associated with holkprosencefalia degree of facial abnormality such as hypotelorism and cleft lip.

Holoprosencephaly – Wikipedia

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Articles Cases Courses Quiz. About Blog Go ad-free. Cases and figures Imaging differential diagnosis. Semilobar holoprosencephaly seen with diffusion tensor imaging and fiber tracking.

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Central Nervous SystemObstetricsGynaecology. Synonyms or Alternate Spellings: Support Radiopaedia and see fewer ads. Case 1 Case 1. Case 2 Case 2. Case 4 Case 4.


Case 5 Case 5. Case 6 Case 6. Holoproaencefalia 7 Case 7. Alobar holoprosencephaly Alobar holoprosencephaly. Lobar holoprosencephaly Lobar holoprosencephaly. Loading Stack – 0 images remaining.